Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome, Hum Mol Genet, vol.16, issue.10, pp.1253-1268, 2007. ,
Identification of stem cells in small intestine and colon by marker gene Lgr5, Nature, vol.449, issue.7165, pp.1003-1007, 2007. ,
Regulation of intestinal epithelial cell growth by transforming growth factor type beta, Proc Natl Acad Sci U S A, vol.86, issue.5, pp.1578-1582, 1989. ,
Cooperation between HNF-1alpha, Cdx2, and GATA-4 in initiating an enterocytic differentiation program in a normal human intestinal epithelial progenitor cell line, Am J Physiol Gastrointest Liver Physiol, vol.298, issue.4, pp.504-517, 2009. ,
Polycomb repressive complex 2 impedes intestinal cell terminal differentiation, J Cell Sci, vol.125, pp.3454-3463, 2012. ,
DNA methylation in stem cell renewal and multipotency, Stem Cell Res Ther, vol.2, issue.5, p.42, 2011. ,
A bivalent chromatin structure marks key developmental genes in embryonic stem cells, Cell, vol.125, issue.2, pp.380-381, 2006. ,
URL : https://hal.archives-ouvertes.fr/hal-02535559
Human embryonic stem cells have a unique epigenetic signature, Genome Res, vol.16, issue.9, pp.1075-1083, 2006. ,
SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes, J Cell Biol, vol.166, issue.1, pp.37-47, 2004. ,
URL : https://hal.archives-ouvertes.fr/hal-00266987
Developmental mucin gene expression in the gastroduodenal tract and accessory digestive glands. I. Stomach. A relationship to gastric carcinoma, J Histochem Cytochem, vol.48, issue.12, pp.1657-1666, 2000. ,
Homeosis and intestinal tumours in Cdx2 mutant mice, Nature, vol.386, issue.6620, pp.84-87, 1997. ,
The intestinal crypt, a prototype stem cell compartment, Cell, vol.154, issue.2, pp.274-284, 2013. ,
Stem cells: a unifying theory for the crypt, Nature, vol.495, issue.7439, pp.53-54, 2013. ,
Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium, J Cell Biol, vol.192, issue.5, pp.767-780, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-02459483
Detection of histone modifications at specific gene loci in single cells in histological sections, Nat Methods, vol.10, issue.2, pp.171-177, 2013. ,
Regulation of the intestinal mucin MUC2 gene expression in vivo: evidence for the role of promoter methylation, Cancer Lett, vol.168, issue.1, pp.71-80, 2001. ,
Induction of apoptosis before shedding of human intestinal epithelial cells, Am J Gastroenterol, vol.97, issue.6, pp.1421-1428, 2002. ,
DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions, Mol Cell Biol, vol.33, issue.9, pp.1463-1475, 2013. ,
Single-molecule transcript counting of stem-cell markers in the mouse intestine, 2012. ,
, Nat Cell Biol, vol.14, issue.1, pp.106-114
DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus, R50, vol.14, 2013. ,
Promoter methylation downregulates CDX2 expression in colorectal carcinomas, Oncol Rep, vol.13, issue.3, pp.547-551, 2005. ,
The human genome browser at UCSC, Genome Res, vol.12, issue.6, pp.996-1006, 2002. ,
Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity, Nature, vol.506, issue.7489, pp.511-515, 2014. ,
Aberrant upregulation of ASCL2 by promoter demethylation promotes the growth and resistance to 5-fluorouracil of gastric cancer cells, Cancer Sci, vol.104, issue.3, pp.391-397, 2013. ,
MethPrimer: designing primers for methylation PCRs, Accessed September, vol.18, issue.11, pp.1427-1431, 2002. ,
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells, Genes Dev, vol.21, issue.20, pp.2545-2557, 2007. ,
DNA methylation: the nuts and bolts of repression, J Cell Physiol, vol.213, issue.2, pp.384-390, 2007. ,
SOX9 is required for the differentiation of Paneth cells in the intestinal epithelium, Gastroenterology, vol.133, issue.2, pp.539-546, 2007. ,
Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1, Cell Stem Cell, vol.6, issue.3, pp.279-286, 2010. ,
Brief demethylation step allows the conversion of adult human skin fibroblasts into insulin-secreting cells, Proc Natl Acad Sci U S A, vol.110, issue.22, pp.8948-8953, 2013. ,
Distinct levels of Sox9 expression mark colon epithelial stem cells that form colonoids in culture, G10-G20, vol.302, 2012. ,
Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells, Proc Natl Acad Sci U S A, vol.105, issue.50, pp.19809-19814, 2008. ,
Bmi1 is expressed in vivo in intestinal stem cells, Nat Genet, vol.40, issue.7, pp.915-920, 2008. ,
Current view: intestinal stem cells and signaling, Gastroenterology, vol.134, issue.3, pp.185-191, 2008. ,
DNA methylation is required for the control of stem cell differentiation in the small intestine, Genes Dev, vol.28, issue.6, pp.652-664, 2014. ,
EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency, Mol Cell, vol.32, issue.4, pp.732-738, 2008. ,
Epigenetics: judge, jury and executioner of stem cell fate, Epigenetics, vol.7, issue.8, pp.823-840, 2012. ,
Biosynthesis of human colonic mucin: Muc2 is the prominent secretory mucin, Gastroenterology, vol.107, issue.5, pp.1352-1363, 1994. ,
Intestinal master transcription factor CDX2 controls chromatin access for partner transcription factor binding, Mol Cell Biol, vol.33, issue.2, pp.1185-1197, 2013. ,
Epigenetics, stem cells and epithelial cell fate, Differentiation, vol.78, issue.2-3, pp.83-91, 2009. ,
On the epigenetic origin of cancer stem cells, Biochim Biophys Acta, vol.1826, issue.1, pp.23-29, 2012. ,
Genome-wide analysis of promoter methylation associated with gene expression profile in pancreatic adenocarcinoma, Clin Cancer Res, vol.17, issue.13, pp.4341-4354, 2011. ,
Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay, Gastroenterology, vol.145, issue.2, 2013. ,