The purpose of this paper is to report, from a qualitative study, the individual and organizational factors and processes that lead an employee to build a unique relationship to is health. We discuss these processes in relation to the construction of health among a sample of 34 „workers” selected in diverse contexts, considering health as a dynamic and co-constructed object. From biographical interviews and records of interactions between workers and professionals who support them, we analyze we analyze the transactions made between work and health. These transactions, which are defined in dynamic and combined processes (psychological, cognitive, interactive and organizational), contribute to define the orientation of the relationship to work, the professional route, and determine the evolution of more objective health status and how it can be seen, lived and managed individually. This article examines three different contexts: small business employees, employees of a large firm, and job seekers. These three contexts are related with different types of strategies implemented by individuals on their health in relation to their position in the world of work.