Loading...
Dernières publications
-
Dylan Moutachi, Janek Hyzewicz, Pauline Roy, Mégane Lemaitre, Damien Bachasson, et al.. Treadmill running and mechanical overloading improved the strength of the plantaris muscle in the dystrophin‐desmin double knockout (DKO) mouse. The Journal of Physiology, In press, ⟨10.1113/JP286425⟩. ⟨hal-04643936⟩
-
Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, et al.. Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy. PLoS ONE, 2024, 19, ⟨10.1371/journal.pone.0295700⟩. ⟨hal-04501283⟩
-
Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, et al.. EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders. Orphanet Journal of Rare Diseases, 2024, 19 (1), pp.66. ⟨10.1186/s13023-024-03059-3⟩. ⟨hal-04460667⟩
-
Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, et al.. Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy - Nucleic Acids, 2023, 32, pp.857 - 871. ⟨10.1016/j.omtn.2023.05.007⟩. ⟨hal-04287597⟩
-
Caroline Le Guiner, T Larcher, A Lafoux, G Toumaniantz, S Webb, et al.. Characterization of the muscular and cardiac diseases of the DMSXL mouse model, a transgenic mouse model for Myotonic Dystrophy type 1. American Society of Gene & Cell Therapy, May 2023, LOS ANGELES, United States. ⟨hal-04096181⟩
-
Dylan Moutachi, Mégane Lemaitre, Clément Delacroix, Onnik Agbulut, Denis Furling, et al.. Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, In press, ⟨10.1111/1440-1681.13804⟩. ⟨hal-04146953⟩
Chiffres clés
139
Publications avec texte intégral
Open Access
53 %
Mots clés
Acetylcholinesterase knockout mouse
Dystrophie Myotonique
Thérapie génique
Glutamate
Myotonic Dystrophy Type 1
DM1
Centronuclear myopathy
Hypoxia
Astrocyte
DMPK
Male
ACETYLCHOLINESTERASE
Therapy
Long read sequencing
Oligodendrocytes
Glucocorticoid-receptor
MBNL
Humans
Gene editing
KNOCKOUT MICE
Transcriptomics
Astrocytes
Animals
Intermediate filament
Oligodendrocyte
Cell model
Exercice
Skeletal muscle
RNA interference
Dystrophin
Motoneuron
CMS
DMSXL mice
Trinucleotide Repeat Expansion
Acute coronary syndrome
Gene Therapy
Mouse model
Quantitative microdialysis
Autophagy
Maximal force
Diaphragm
Mice
Duchenne muscular dystrophy
Central nervous system
Fibrosis
Heart
Knockout
Acetylcholinesterase deficiency
BIOLOGIE MOLECULAIRE
Mouse models
Heart failure
RNA splicing
Myotonic Dystrophy
CTG repeat instability
Cardiac muscle
Muscle
In vivo
Muscular dystrophy
Alternative splicing
Expression
Glucocorticoids
Dilated cardiomyopathy
Exercise
Brain dysfunction
Transgenic mouse model
Gene therapy
Dystrophie myotonique
Cell culture model
AAV
CTG repeats
Myotonic dystrophy mouse models
PCR
Myotonic Dystrophy type 1
Aging
Myotonic dystrophy
GABA
GSK3
Cytoskeleton
Transgenic mouse
CTG repeat contractions
Trinucleotide repeat expansion
PacBio
Neuron
RNA biology
Dynamin 2
CRISPRi
CRISPR/Cas9
ARN
Antisense oligonucleotide
Endurance training
Glial cells
Antisense oligonucleotides
Brain
Cell penetrating peptide
Myostatin
Myelin
CONGENITAL MYATHENIC SYNDROME
Desmin
Myotonic dystrophy type 1
Genotype phenotype correlation