This study addresses how salience shapes the perceptual organization of an auditory scene. A psychophysical task that was introduced previously by Susini, Jiaouan, Brunet, Houix, and Ponsot [(2020). Sci. Rep. 10(1), 16390] was adapted to assess how the ability of non-musicians and expert musicians to detect local/global contour changes in simple hierarchically-organized tone sequences is affected by the relative salience of local information in the timbre dimension. Overall, results show that salience enhanced local processing capacities, at the cost of global processing, suggesting a bottom-up reallocation of attention. Interestingly, for non-musicians, salience caused a reversal of the basic global-over-local processing prioritization as it is typically observed in expert musicians.